Chemistry and Biochemistry

CHEM 110 SURVEY OF GENERAL CHEMISTRY - 5 hrs
Lecture and laboratory
A study of inorganic chemistry including atoms, energy, bonding, reactions, states of matter, and calculations. Coreq: MATH 115.

CHEM 220 SURVEY OF BIO-ORGANIC CHEMISTRY - 6 hrs
A survey course covering a range of topics for the non-major. The first forty percent of the class will serve as an overview of the major organic functional groups found in biochemistry. The latter sixty percent will focus on metabolism, the properties of biomolecules, and the chemistry of biological processes. Throughout the course examples will be cited of the biochemical basis of disease and current pharmaceutical treatments of these disorders. Prereq: CHEM 110. Note: Chemistry 110 and 220 do not count toward a Chemistry major or minor.

CHEM 140 GENERAL CHEMISTRY I - 3 hrs
The first course in a three quarter sequence to introduce basic concepts of chemistry to students majoring in science. Emphasis on problem solving and developing scientific thought processes. Course content includes atomic properties, basic calculations, thermochemistry, aqueous reactions, gas laws, and intermolecular forces. Prereq: One year of high school chemistry or CHEM 110. Coreq: MATH 115 or 120.

CHEM 141 GENERAL CHEMISTRY I LABORATORY - 1 hr
The laboratory is designed to reinforce concepts from lecture and develop experimental skills. Quantitative and synthesis experiments are included with emphasis on report writing. Coreq: CHEM 140 that must be taken at Otterbein College.

CHEM 150 GENERAL CHEMISTRY II - 3 hrs
Continuation of Chemistry 140. Course content includes the structure of atoms and molecules, chemical bonding, thermodynamics, solution stoichiometry, and kinetics. Prereq: CHEM 140. Coreq: MATH 116 or 120.

CHEM 151 GENERAL CHEMISTRY II LABORATORY - 1 hr
Continuation of Chemistry 141. Laboratory and computer-based experiments are performed to clarify and reinforce lecture topics. Prereq: CHEM 141. Coreq: CHEM 150 that must be taken at Otterbein College.

CHEM 160 GENERAL CHEMISTRY III - 3 hrs
Continuation of Chemistry 150. Inorganic and analytical topics include acid-base equilibria, solubility, complex ion formation, electron transfer reactions, and an introduction to qualitative inorganic chemistry. Prereq: CHEM 150.

CHEM 161 GENERAL CHEMISTRY III LABORATORY - 1 hr
Continuation of Chemistry 151, with emphasis on inorganic synthesis, equilibrium studies, and qualitative analysis. Prereq: CHEM 151. Coreq: CHEM 160 that must be taken at Otterbein College.

CHEM 240 ORGANIC CHEMISTRY I - 3 hrs
Structure, reactivity, and synthesis of carbon-containing compounds. The problem-solving approach emphasizes the correlation of reaction mechanism with modern structural theory. Topics include the nature of bonding, stereochemistry, alkanes, alkenes, and alkynes. Prereq: CHEM 160.

CHEM 241 ORGANIC CHEMISTRY I LABORATORY - 1 hr
Experimental techniques are introduced in the laboratory through isolation of natural products, preparation of representative functional compounds, and multistep synthesis of complex molecules. Prereq: CHEM 161; Coreq: CHEM 240 that must be taken at Otterbein College.

CHEM 250 ORGANIC CHEMISTRY II - 3 hrs
Continuation of Chemistry 240, including a discussion of alkyl halides, spectroscopy, aromaticity, alcohols, ethers, aldehydes and ketones. Prereq: CHEM 240.

CHEM 251 ORGANIC CHEMISTRY II LABORATORY - 1 hr
Continuation of Chemistry 241. Prereq: CHEM 241. Coreq: CHEM 250 that must be taken at Otterbein College.

CHEM 260 ORGANIC CHEMISTRY III - 3 hrs
Continuation of Chemistry 250, including a discussion of carboxylic acids and their derivatives, carbonyl condensation reactions, amines, and polymers. Prereq: CHEM 250.

CHEM 261 ORGANIC CHEMISTRY III LABORATORY - 1 hr
Continuation of Chemistry 251, emphasizing classical and modern qualitative analysis. Prereq: CHEM 251. Coreq: CHEM 260 that must be taken at Otterbein College.

CHEM 265 INTRODUCTION TO BIOCHEMICAL TECHNIQUES - 2 hrs
This course introduces basic modern biochemical laboratory techniques to sophomores intending to pursue a career in biochemistry or related fields.  It is highly suggested for students wishing to conduct undergraduate research in biochemistry.  Topics covered include the analysis and separation of biological macromolecules (DNA and protein), biological database analysis, and enzyme kinetics.  Prereq: CHEM 240/241

CHEM 270 INORGANIC CHEMISTRY - 3 hrs
Survey of the properties and reactivity of main group and transition metal elements. Topics include atomic structure and bonding theory, introduction to molecular orbital theory, acid-base theories, inorganic nomenclature, coordination chemistry, periodic properties of the elements, and basic organometallic chemistry. Prereq: CHEM 160 and 161.

CHEM 271 INORGANIC CHEMISTRY LABORATORY - 2 hrs
Synthesis and characterization of organometallic, coordination, bioinorganic and solid state compounds. Includes inert atmosphere techniques, vibrational spectroscopy, multi-nuclear NMR spectroscopy, and electrochemistry. Coreq: CHEM 270 that must be taken at Otterbein College.

CHEM 280 ANALYTICAL CHEMISTRY - 5 hrs
Lecture and laboratory
A cornerstone course for developing skills in scientific measurement, analysis, and report writing, designed to train students in quantitative skills using statistical data analysis and computer programs, with an emphasis on spreadsheet computations. Basic skills in volumetric and potentiometric titrations, spectrophotometric analyses, and modern instrumental analysis techniques are taught. Prereq: MATH 170, CHEM 160 and 161.

CHEM 330 BIOPHYSICAL CHEMISTRY - 6 hrs
A survey of the application of thermodynamics, kinetics, quantum mechanics, spectroscopy applied to biochemical systems. This course has a laboratory component. Prereq: MATH 180 and PHYS 173. Coreq: CHEM 280.

CHEM 340 PHYSICAL CHEMISTRY I - 5 hrs
This course is the first in the physical chemistry series. It covers gas laws, thermodynamics, kinetics, and molecular motion. Prereq: MATH 180 and PHYS 173. Coreq: CHEM 280.

CHEM 341 PHYSICAL CHEMISTRY I LABORATORY - 1 hr
Laboratory applications of the fundamental principles of thermodynamics are demonstrated. Hypothesis testing and the critical analysis of data by mathematical modeling are stressed. In addition, scientific writing skills of publication-quality papers are developed. Coreq: CHEM 340 that must be taken at Otterbein College.

CHEM 350 PHYSICAL CHEMISTRY II - 5 hrs
This course is the second in the physical chemistry series. It covers quantum mechanics, spectroscopy, and statistical mechanics. Prereq: MATH 200, PHYS 173, CHEM 340.

CHEM 351 PHYSICAL CHEMISTRY II LABORATORY - 1 hr
Laboratory applications of quantum mechanics are demonstrated primarily by connecting the model calculations of the classroom exercises with spectroscopic measurements. Ultraviolet-visible (UV-VIS), infrared (IR), Raman, and nuclear magnetic resonance (NMR) spectroscopies are utilized to demonstrate the principles of quantum mechanics. Scientific writing skills are further developed. Coreq: CHEM 350 that must be taken at Otterbein College.

CHEM 380 INSTRUMENTAL ANALYSIS - 5 hrs
Lecture and laboratory
A study of the theory and applications of modern chemical instrumentation. Includes UV-VIS, FT-IR, FT-NMR, Raman, and atomic absorption spectroscopies, gas and liquid chromatography, GC-MS, electroanalytical techniques, and computer interfacing. Ability to use computer spreadsheet programs and knowledge of basic statistical analysis are assumed. Prereq: CHEM 280.

CHEM 390 INDEPENDENT STUDY - 1-4 hrs
A student undertakes a research problem with the consent of a staff member and, if repeated, may receive up to 4 hrs of credit. Prereq: CHEM 261 or 341.

CHEM 400 SEMINAR - 2 hrs
An introduction to on-line searching of the chemical literature, oral presentations, a term paper on a specific topic, and periodic guest lectures. Taken each term in the senior year. Prereq: CHEM 340.

CHEM 410 POLYMER CHEMISTRY - 3 hrs
An introduction to polymer science including monomer and polymer syntheses, polymerization kinetics, molecular weight distribution, and physical properties including thermal, viscoelastic properties, solubilities, and miscibilities. Polymer molecular modeling will be introduced to predict physical properties of polymers built in the modeling program as an alternative to a laboratory module. Prereq: CHEM 260 and 340, or permission of the instructor.

CHEM 440 ADVANCED ORGANIC CHEMISTRY - 3 hrs
Advanced reaction mechanisms, kinetics, structure-reactivity relationships, orbital symmetry considerations, and newer synthetic methods are presented. Prereq: CHEM 260 and 340.

CHEM 450 BIOCHEMISTRY I - 3 hrs
A discussion of the general physical and chemical properties of amino acids, proteins (including enzymes), carbohydrates, and nucleic acids, with an emphasis on structure-reactivity correlations and reaction mechanisms. Prereq: CHEM 260.

CHEM 460 BIOCHEMISTRY II - 3 hrs
Continuation of Chemistry 450, including an analysis of intermediary metabolism and other important biological reactions from an organic chemistry multifunctional group perspective. Prereq: CHEM 450.

CHEM 465 ADVANCED BIOCHEMISTRY - 4 hrs
Lecture and laboratory
An advanced course dedicated to a thorough examination of biological processes at the chemical level. Five units will be studied consisting of protein structure and function, enzyme kinetics, bioinformatics and data mining, signal transduction and second messengers, and neuroscience and electrophysiology. Topics will be addressed using graduate level texts and reviews of current literature. Laboratory sections and take home exercises will complement material covered in lecture. Prereq: CHEM 280 and 460.

CHEM 470 ADVANCED INORGANIC CHEMISTRY - 3 hrs
In depth treatment of advanced topics in inorganic chemistry, including quantum theory, group-theory, advanced bonding theory, electronic spectra, magnetism, organotransition metal chemistry, bioinorganic chemistry, catalysis, and an introduction to band-theory in solids. Prereq: CHEM 270 and 340.

CHEM 480 SPECIAL TOPICS - 2-4 hrs
Topics not included in the regular curriculum. Prereq: depends on the specific topic.

CHEM 490 INTERNSHIP - 1-15 hrs
Employment experience off-campus. Approved, arranged and administered by the department. Not applicable as credit for the major.